Brain tumors remain a significant health problem in the worldwide. Overall, they comprise some of the most malignant tumors known to affect human beings and are generally refractory to all modalities of treatment. Angiogenesis underlies all tumor growth by providing […]
Perfusion is a fundamental biological function that refers to the delivery of oxygen and nutrients to tissue by means of blood flow .Perfusion MRI is sensitive to microvasculature and has been applied in a wide variety of clinical applications, including the […]
The calculation of perfusion analysis is based on measurements taken while the bolus travels through the blood system. The starting point is the arterial input function (AIF), measured at the artery before the contrast agent bolus travels through the region […]
Diffusion-weighted imaging (DWI) is a form of MR imaging based upon measuring the random Brownian motion of water molecules within a voxel of tissue. In general simplified terms, highly cellular tissues or those with cellular swelling exhibit lower diffusion coefficients. […]
Functional magnetic resonance imaging (fMRI) measures the small changes in blood flow that occur with brain activity. It may be used to examine the brain’s functional anatomy, (determine which parts of the brain are handling critical functions), evaluate the effects […]
After designing an fMRI paradigm and running the experiment and the data collection, various analysis steps must be applied on resulting data before the neuroscientists and physicians can achieve answers to the questions about activities corresponding to the experiment. The […]
Diffusion Tensor Imaging (DTI) is an magnetic resonance imaging‑based neuroimaging technique that makes it possible to estimate the location, orientation, and anisotropy of the white matter tracts of the brain. (DTI) is an MRI technique that measures water molecule diffusion […]
DTI Analysis Techniques Many different DTI analysis techniques and approaches have been applied to study a range of pathologies and include region of interest analysis, tractography, histogram analysis, atlas-based segmentation, quantification of graph-based connectivity networks, and voxel-based analysis to name […]
Brain mapping When operating on brain tumors, it is critical to avoid damaging the brain regions responsible for language, motor, and sensory function. While we know which parts of the brain are responsible for these functions (and where they’re generally […]