
KIO Quantitative Biomarkers
KIO Medical by using BIOQUANT quantification modules combines the company’s innovative technology with a holistic view of patient data (BIOQUANT derived markers) to enable clinicians to make reliable, evidence-based diagnostic and management decisions for their patients.
Discover BIOQUANT; a solution that accelerates radiologist workflow by generating MRI analysis through automating the segmentation process in just a moment!
Quantification Oriented
Fully automated, reliable, reproducible analysis of brain atrophy:
- Volumes of 12 cortical and subcortical regions (T1)
- Quantification of longitudinal changes in brain structure atrophy
- Comparison of results to normative reference data adjusted for age and intracranial volume with results presented in tabular form or as age-corrected plots
- Interactive image review, with the ability to compare multiple time points
Fully automated, reliable, reproducible analysis of brain white matter hyperintensity:
- White-matter hyper-intensity segmentation (T2-FLAIR)
- Quantification of longitudinal changes in brain lesion changes and segmentations
- Comparison of results to normative reference data adjusted for age and intracranial volume with results presented in tabular form plots
- Interactive image review, with the ability to compare multiple time points
Fully automated, reliable, reproducible analysis of brain perfusion (DSC, DCE):
- Providing pharmacokinetic parameters using DCE module (Blood Flow (BF), Blood Volume (BV), Mean Transit Time (MTT)] and permeability parameters [including endothelial transfer constant (Ktrans), reflux rate (Kep), fractional extravascular extracellular space volume (Ve), fractional plasma volume (Vp))
- Calculate parameters rCBV, rCBF, and MTT using the DSC module
- Quantification of longitudinal changes in brain perfusion
- Interactive image review, with the ability to compare multiple time points
Benefits Oriented
Increase sensitivity
- Identify subtle, disease-specific changes and patterns in brain volume and/or lesions that are difficult to detect using visual assessment alone
Improve collaboration and referrals
- Improve collaboration, provide greater value, reduce image-related queries, and drive more referrals through streamlined, high-quality, consistent communication with referring clinicians
Reclaim time
- Increase throughput by reducing the time spent per image read, without compromising on quality.


Automated analysis
Extract clinically quantitative data from MRI images automatically

Reference curves
Compared quantitative volumes with standard limitations

Standardized reporting
Generates objective meaningful insights from MRI exams

Time saving
Reduce reading time and streamlines radiology workflow
KIO Medical Workflow

Cloud-based computation algorithms to quantify specific feature of brain abnormality in dementia, integrates with PACS, and results can be viewed in browser-based viewer.
Radiologists benefit from enhanced accuracy, results compared to reference curves, access to previous results for longitudinal comparison, automated changes computed within two time points, and finally, reduced time spent per scan.
Neurologist benefits from an online DICOM viewer, fast access to patient history (quantification findings, radiologist report), communication with colleagues in emergency scenarios, and finally, patient data management.

Power your research and clinical data with cloud data management system
Quantification Modules
Medical Images Viewer
Collaborate Globally and Share Data Easily



Automated quantification module for assessment of functional parameters of lesions
Quantification Results
Longitudinal Compare
Structured Report

AI-powered cloud-based solution to data collection, quality control and analysis, letting you focus on what matters most
Develop your own module
